Benyi Li, M.D., PhD. - Publications

• Qin Zhu, Jianxi Tang, Hyewon Youn, Ossama Tawfik, Paul F. Terranova, Jie Du, Patrick Raynal, J. Brantley Thrasher, Li B: Phosphoinositide 3-OH kinase p110? is Essential for Androgen Receptor Transactivation and Tumor Growth in Prostate Cancer. Oncogene 2008, In Press.
• Aijing Sun, Jianxi Tang, Yan Hong, Jiawu Song, Paul F. Terranova, J. Brantley Thrasher, Stan Svojanovsky, Hong-gang Wang, Li B: Androgen Receptor-dependent Regulation of Bcl-xL Expression: Implication in Prostate Cancer Progression. The Prostate 2008, In Press.
• Ilanchezhian Shanmugam, Guangming Cheng, Paul F. Terranova, J. Brantley Thrasher, Christie P. Thomas, Li B: Serum/Glucocorticoid-induced Protein Kinase-1 Facilitates Androgen Receptor-dependent Cell Survival. Cell Death and Differentiation, 14(2):2085-2094 2007.
• Aijing Sun, Ilanchezian Shanmugam, Hyewon Youn, Jiawu Song, Paul F. Terranova, J. Brantley Thrasher, Li B: Lithium Suppress Cell Proliferation and E2F-mediated Gene Expression by Disrupting E2F-DNA Interaction in Prostate Cancer Cells. The Prostate 67(9):976-988, 2007.
• Li B, Aijing Sun, Hyewon Youn, Yan Hong, Paul F. Terranova, J. Brantley Thrasher, Pingyi Xu: Conditional Akt Activation Promotes Androgen-independent Progression of Prostate Cancer. Carcinogenesis 28(3):572-83, 2007.
• Li B, Liao XB, Fujito A, Thrasher JB, Shen F, Xu PY: Dual Androgen-response Elements Mediate Androgen Regulation of mmp-2 Gene Expression in Prostate Cancer Cells. Asian Journal of Andrology 9(1):41-50, 2007.
• Sun A, Tawfik O, Geyrad B, Thrasher JB, Hoesije, S, Li C and Li B: Aberrant Expression of SWI/SNF Catalytic Subunits BRG1/BRM is Associated with Tumor Development and Increased Invasiveness in Prostate Cancers. The Prostate 67(2):203-13, 2007.
• Chen L, Meng S, Wang H, Bali P, Bai W, Li B, Atadja P, Bhalla KN, Wu J: Chemical Ablation of Androgen Receptor in Prostate Cancer Cells by the Histone Deacetylase Inhibitor LAQ824. Mol Cancer Ther 4(9):1311-9, 2005.
• Liao X, Tang S, Griebling T, Thrasher JB, Li B: siRNA-mediated Androgen Receptor Silencing Leads to Apoptotic Cell Death in Prostate Cancer. Mol Cancer Therapeutics 4(4):505-15, 2005.
• Liao X, Thrasher JB, Holzbeierlein J, Scott S, Li B: GSK-3? Activity is Required for Androgen-Stimulated Gene Expression. Endocrinology 145:2941-2949, 2004.
• Liao X, Zhang L, Du J, Thrasher JB, Li B: GSK-3? Suppression Eliminates TRAIL Resistance in Prostate Cancer. Mol Cancer Therapeutics 2:1215-1222, 2003.
• Liao X, Thrasher JB, Pelling J, Sang QX, Holzbeierlein JM, Li, B: Androgen Stimulates MMP2 Expression in Human Prostate Cancer. Endocrinology 144:1656-1663, 2003.
• Li B, Desai, SA, MacCorkle-Chosnek, RA, Fan, L, Spencer, DM: A Novel Conditional Akt 'Survival Switch' Reversibly Protects Cells from Apoptosis. Gene Ther 9(4):233-244, 2002
• Li B, QP Dou: Bax Degradation by the Ubiquitin/proteasome Pathway: Involvement in Tumor Survival and Progression. Proceedings of National Academy Society of USA 97:3850-3855, 2000.
• Dou QP, Li B: Proteasome Inhibitors as Potential Anticancer Agent. Drug Resistant Updates 2:215-233, 1999.
• Sun JZ, Nam S, Lee CS, Li, B, et al: CEP1612, a Dipeptidyl Proteasome Inhibitor, Induces p21waf1 and p27kip1 Expression and Apoptosis and Inhibits the Growth of the Human Lung Adenocarcinoma A-549 in Nude Mice. Cancer Research 61:1280-1284. 2000.
• Kanamaru H, Li B, et al: Immunohistochemical Expression of p53 and bcl-2 Proteins is not Associated with Sarcomatoid Change in Renal Cell Carcinoma. Urological Research 27:169-173, 1999.
• Li, et al: Different Expression of Hepatocyte Growth Factor in Papillary and Nodular Tumors of the Bladder. Intl Journal of Urology 5:436-440, 1998.
• Tsuka H, Mori H, Li B, et al: Enhanced Hepatocyte Growth Factor Level in Human Prostate Cancer Treated with Endocrine Therapy. International Journal of Oncology 13:169-176,1998.
• Li B, et al: Numerical Aberration of Chromosome 17 is Strongly Correlated with p53 Expression, Tumor Proliferation and Histopathology. International Journal of Urology 5:317-323, 1998.
• Tsuka H, Mori H, Li B, et al: Expression of c-Met/HGF Receptor mRNA and Protein in Human Non-malignant and Malignant Prostate Tissue. International Journal of Oncology 13:927-934, 1998.
• Li B, et al: Reciprocal Expression of bcl-2 and p53 Oncoproteins in Urothelial Dysplasia and Carcinoma of the Urinary Bladder. Urological Research 26:235-241, 1998.
• Li B, et al: Increased Cell Proliferation of Urothelium in Rat Bladder Following Unilateral Nephrotectomy. J Urol 158:265, 1997.
• Sato K, Kusaka Y, Zhang Q, Deguchi Y, and Li B, et al: Direct Effect of Inorganic Mercury on Citrate Uptake by Isolated Rat Renal Brush Border Membrane Vesicles. Industrial Health 35:456, 1997.
• Sato K, Kusaka Y, Zhang Q, Li B, et al: Citrate Uptake by Isolated Rat Renal Brush Border Membrane Vesicles in Cadmium-Intoxicated Rats. Industrial Health 35:388, 1997.
• Saikawa, H, Kanamaru H, Li B, et al: Promoting Effect of Unilateral Nephrotectomy on Urinary Bladder Carcinogenesis in Rats. Japanese Journal of Cancer Research 87:1121, 1996.
• Li B, et al: Protective Effects of Nifidipine and Allopurinal on HESW-Induced Acute Changes of Renal Runction. J Urol 153:596, 1995.
• Li B, et al: The relationship Between the Levels of ESWL and the Degree of Renal Damage: a Prospective Clinical Matching Trial. Journal of Tongji Medical University 14:114, 1994.
• Li B et al: HESW Induced Acute Changes of Renal Function. Chinese Medical Journal 72:525-527, 1992.
• Li B, et al: Acute Changes of Glomerular and Tubular Function Induced by HESW. Chinese Clinical Journal of Urology 7:93-95, 1992.
• Zhou XC, Li B, et al: Acute Changes and Clinical Significance of PGI2 and TXA2 in Plasma and Urine Following ESWL in Patient with Nephrolithiasis. Chinese Journal of Experimental Surgery 11:195-197, 1994.
• Li B, et al: The Relation of Energy Level of HESW with Renal Injury. Chinese Journal of Experimental Surgery 11:75-76, 1994.
• Li B, et al: Nifedipine and Allopurinal Protect Renal Function During ESWL. Chinese Medical Journal 75:284-285, 1995.
• Li B, Zhou XC: The Advances in HESW Study. Chinese Clinical Journal of Urology 6:239-242, 1991.
• Li B, Zhang YC: Inhibitin and Male Fertility. Journal of Foreign Medicine in Urology 12:7-9, 1992.
• Li B, Zhang YC: Current Status in Nephrocalcin Study. Journal of Foreign Medicine in Urology 14:38-40, 1994.
• Li B, Zhang YC: Peptide Growth Factors and its Receptors in Benign Prostate Hyperplasia. Journal of Foreign Medicine in Urology15:7-10, 1995.
• Li B, Zhang YC: The Recent Management of Adrenal Incidentaloma. Journal of Foreign Medicine in Urology 16:2.-23, 1996.
• Li B Zhang YC: The Application of Melatonin in Urology. Journal of Foreign Medicine in Urology 17:254-257, 1997.
• Li B, Zhang YC: Telomere, Telomerase and Urological Cancer. Journal of Foreign Medicine in Urology 18:27-30, 1998.